1dsx

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[[Image:1dsx.png|left|200px]]
 
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{{STRUCTURE_1dsx| PDB=1dsx | SCENE= }}
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==KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT==
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<StructureSection load='1dsx' size='340' side='right'caption='[[1dsx]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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===KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dsx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DSX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11007484}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dsx OCA], [https://pdbe.org/1dsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dsx RCSB], [https://www.ebi.ac.uk/pdbsum/1dsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dsx ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1dsx]] is a 8 chain structure of [[Potassium Channel]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DSX OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/KCNA2_RAT KCNA2_RAT] Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.<ref>PMID:7544443</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/1dsx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dsx ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Potassium Channel|Potassium Channel]]
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*[[Potassium channel 3D structures|Potassium channel 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011007484</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Avelar, A.]]
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[[Category: Avelar A]]
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[[Category: Berger, J M.]]
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[[Category: Berger JM]]
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[[Category: Jan, L Y.]]
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[[Category: Jan LY]]
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[[Category: Jan, Y N.]]
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[[Category: Jan YN]]
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[[Category: Lin, Y F.]]
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[[Category: Lin Y-F]]
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[[Category: Minor, D L.]]
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[[Category: Minor Jr DL]]
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[[Category: Mobley, B C.]]
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[[Category: Mobley BC]]
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[[Category: Assembly domain]]
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[[Category: Signaling protein]]
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[[Category: Tetramer]]
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[[Category: Voltage-gated potassium channel]]
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Current revision

KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT

PDB ID 1dsx

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