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1n59

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[[Image:1n59.png|left|200px]]
 
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{{STRUCTURE_1n59| PDB=1n59 | SCENE= }}
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==Crystal structure of the Murine class I Major Histocompatibility Complex of H-2KB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV==
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<StructureSection load='1n59' size='340' side='right'caption='[[1n59]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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===Crystal structure of the Murine class I Major Histocompatibility Complex of H-2KB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n59]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_mammarenavirus Lymphocytic choriomeningitis mammarenavirus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N59 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12479822}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n59 OCA], [https://pdbe.org/1n59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n59 RCSB], [https://www.ebi.ac.uk/pdbsum/1n59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n59 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1n59]] is a 6 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N59 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n5/1n59_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n59 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012479822</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Lymphocytic choriomeningitis mammarenavirus]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Achour, A.]]
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[[Category: Achour A]]
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[[Category: Grufman, P.]]
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[[Category: Grufman P]]
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[[Category: Harris, R A.]]
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[[Category: Harris RA]]
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[[Category: Karre, K.]]
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[[Category: Karre K]]
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[[Category: Levitsky, V.]]
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[[Category: Levitsky V]]
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[[Category: Michaelsson, J.]]
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[[Category: Michaelsson J]]
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[[Category: Odeberg, J.]]
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[[Category: Odeberg J]]
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[[Category: Sandalova, T.]]
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[[Category: Sandalova T]]
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[[Category: Sandberg, J K.]]
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[[Category: Sandberg JK]]
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[[Category: Schneider, G.]]
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[[Category: Schneider G]]
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[[Category: Immune system]]
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[[Category: Immunodominant epitope]]
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[[Category: Lcmv]]
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[[Category: Murine mhc]]
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[[Category: Viral escape]]
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Current revision

Crystal structure of the Murine class I Major Histocompatibility Complex of H-2KB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV

PDB ID 1n59

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