1dxi

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[[Image:1dxi.gif|left|200px]]<br /><applet load="1dxi" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1dxi, resolution 2.6&Aring;" />
 
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'''STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION'''<br />
 
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==Overview==
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==STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION==
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Glucose isomerase from Streptomyces murinus has been crystallized in space group P4(1)2(1)2, cell dimensions a = b = 137.65 and c = 132.20 A. One dimer of the tetrametric molecule is found per asymmetric unit. An initial structure solution was obtained by the molecular replacement method. The crystallographic refinement was performed using molecular dynamics techniques with X-ray restraints. The final crystallographic R value is 21.4% at 2.6 A resolution including 3023 non-H atoms, two metal ions and two water molecules per monomer.
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<StructureSection load='1dxi' size='340' side='right'caption='[[1dxi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dxi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_murinus Streptomyces murinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DXI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dxi OCA], [https://pdbe.org/1dxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dxi RCSB], [https://www.ebi.ac.uk/pdbsum/1dxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dxi ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XYLA_STRMR XYLA_STRMR] Involved in D-xylose catabolism.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/1dxi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dxi ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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1DXI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_murinus Streptomyces murinus] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXI OCA].
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*[[D-xylose isomerase 3D structures|D-xylose isomerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Structure determination of glucose isomerase from Streptomyces murinus at 2.6 A resolution., Rasmussen H, la Cour T, Nyborg J, Schulein M, Acta Crystallogr D Biol Crystallogr. 1994 Mar 1;50(Pt 2):124-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299450 15299450]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Streptomyces murinus]]
[[Category: Streptomyces murinus]]
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[[Category: Xylose isomerase]]
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[[Category: La Cour T]]
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[[Category: Cour, T La.]]
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[[Category: Nyborg J]]
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[[Category: Nyborg, J.]]
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[[Category: Rasmussen H]]
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[[Category: Rasmussen, H.]]
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[[Category: Schulein M]]
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[[Category: Schulein, M.]]
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[[Category: MG]]
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[[Category: isomerase(intramolecular oxidoreductase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:21:31 2008''
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Current revision

STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION

PDB ID 1dxi

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