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3lcl

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[[Image:3lcl.png|left|200px]]
 
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{{STRUCTURE_3lcl| PDB=3lcl | SCENE= }}
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==The D-sialic acid aldolase mutant V251I/V265I==
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<StructureSection load='3lcl' size='340' side='right'caption='[[3lcl]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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===The D-sialic acid aldolase mutant V251I/V265I===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3lcl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LCL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[3lcl]] is a 4 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCL OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lcl OCA], [https://pdbe.org/3lcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lcl RCSB], [https://www.ebi.ac.uk/pdbsum/3lcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lcl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]
==See Also==
==See Also==
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*[[Aldolase|Aldolase]]
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*[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]]
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[[Category: Escherichia coli]]
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__TOC__
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[[Category: N-acetylneuraminate lyase]]
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</StructureSection>
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[[Category: Chou, C Y.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ko, T P.]]
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[[Category: Large Structures]]
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[[Category: Wang, A H.J.]]
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[[Category: Chou C-Y]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Ko T-P]]
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[[Category: Lyase]]
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[[Category: Wang AH-J]]
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[[Category: Schiff base]]
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[[Category: Tim barrel]]
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Current revision

The D-sialic acid aldolase mutant V251I/V265I

PDB ID 3lcl

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