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1m04

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[[Image:1m04.png|left|200px]]
 
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{{STRUCTURE_1m04| PDB=1m04 | SCENE= }}
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==Mutant Streptomyces plicatus beta-hexosaminidase (D313N) in complex with product (GlcNAc)==
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<StructureSection load='1m04' size='340' side='right'caption='[[1m04]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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===Mutant Streptomyces plicatus beta-hexosaminidase (D313N) in complex with product (GlcNAc)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_plicatus Streptomyces plicatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M04 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12171933}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m04 OCA], [https://pdbe.org/1m04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m04 RCSB], [https://www.ebi.ac.uk/pdbsum/1m04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m04 ProSAT]</span></td></tr>
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[[1m04]] is a 1 chain structure of [[Beta-Hexosaminidase]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_plicatus Streptomyces plicatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M04 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O85361_STRPL O85361_STRPL]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m0/1m04_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m04 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
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*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
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==Reference==
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*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
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<ref group="xtra">PMID:012171933</ref><references group="xtra"/>
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__TOC__
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[[Category: Beta-N-acetylhexosaminidase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces plicatus]]
[[Category: Streptomyces plicatus]]
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[[Category: James, M N.G.]]
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[[Category: James MNG]]
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[[Category: Mark, B L.]]
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[[Category: Mark BL]]
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[[Category: Vocadlo, D J.]]
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[[Category: Vocadlo DJ]]
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[[Category: Williams, S J.]]
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[[Category: Williams SJ]]
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[[Category: Withers, S G.]]
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[[Category: Withers SG]]
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[[Category: Family 20 glycosidase]]
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[[Category: Hexosaminidase]]
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[[Category: Hydrolase]]
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[[Category: Substrate assisted catalysis]]
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Current revision

Mutant Streptomyces plicatus beta-hexosaminidase (D313N) in complex with product (GlcNAc)

PDB ID 1m04

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OCA

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