1hta

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[[Image:1hta.png|left|200px]]
 
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{{STRUCTURE_1hta| PDB=1hta | SCENE= }}
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==CRYSTAL STRUCTURE OF THE HISTONE HMFA FROM METHANOTHERMUS FERVIDUS==
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<StructureSection load='1hta' size='340' side='right'caption='[[1hta]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE HISTONE HMFA FROM METHANOTHERMUS FERVIDUS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1hta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermus_fervidus Methanothermus fervidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HTA FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11021968}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hta OCA], [https://pdbe.org/1hta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hta RCSB], [https://www.ebi.ac.uk/pdbsum/1hta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hta ProSAT]</span></td></tr>
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[[1hta]] is a 1 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Methanothermus_fervidus Methanothermus fervidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTA OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HMFA_METFE HMFA_METFE] Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1hta_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hta ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Archaeal Histones|Archaeal Histones]]
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*[[Histone 3D structures|Histone 3D structures]]
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*[[Histone|Histone]]
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:011021968</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Methanothermus fervidus]]
[[Category: Methanothermus fervidus]]
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[[Category: Decanniere, K.]]
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[[Category: Decanniere K]]
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[[Category: Heinemann, U.]]
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[[Category: Heinemann U]]
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[[Category: Reeve, J N.]]
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[[Category: Reeve JN]]
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[[Category: Sandman, K.]]
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[[Category: Sandman K]]
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[[Category: Histone]]
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Current revision

CRYSTAL STRUCTURE OF THE HISTONE HMFA FROM METHANOTHERMUS FERVIDUS

PDB ID 1hta

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