1trk

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[[Image:1trk.png|left|200px]]
 
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{{STRUCTURE_1trk| PDB=1trk | SCENE= }}
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==REFINED STRUCTURE OF TRANSKETOLASE FROM SACCHAROMYCES CEREVISIAE AT 2.0 ANGSTROMS RESOLUTION==
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<StructureSection load='1trk' size='340' side='right'caption='[[1trk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===REFINED STRUCTURE OF TRANSKETOLASE FROM SACCHAROMYCES CEREVISIAE AT 2.0 ANGSTROMS RESOLUTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1trk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TRK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8176731}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1trk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1trk OCA], [https://pdbe.org/1trk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1trk RCSB], [https://www.ebi.ac.uk/pdbsum/1trk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1trk ProSAT]</span></td></tr>
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[[1trk]] is a 2 chain structure of [[Transketolase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TRK OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TKT1_YEAST TKT1_YEAST] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.<ref>PMID:8521838</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tr/1trk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1trk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Transketolase|Transketolase]]
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*[[Transketolase 3D structures|Transketolase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:008176731</ref><ref group="xtra">PMID:011170211</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Transketolase]]
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[[Category: Lindqvist Y]]
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[[Category: Lindqvist, Y.]]
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[[Category: Nikkola M]]
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[[Category: Nikkola, M.]]
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[[Category: Schneider G]]
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[[Category: Schneider, G.]]
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Current revision

REFINED STRUCTURE OF TRANSKETOLASE FROM SACCHAROMYCES CEREVISIAE AT 2.0 ANGSTROMS RESOLUTION

PDB ID 1trk

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