3ge1
From Proteopedia
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- | [[Image:3ge1.png|left|200px]] | ||
- | + | ==2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol== | |
- | + | <StructureSection load='3ge1' size='340' side='right'caption='[[3ge1]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GE1 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
- | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
- | [[3ge1]] is a 4 chain structure | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [https://pdbe.org/3ge1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ge1 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GLPK_STAAC GLPK_STAAC] Key enzsyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate (By similarity).[HAMAP-Rule:MF_00186] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3ge1_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ge1 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Glycerol kinase|Glycerol kinase]] | *[[Glycerol kinase|Glycerol kinase]] | ||
- | [[Category: | + | __TOC__ |
- | [[Category: Staphylococcus aureus subsp. aureus | + | </StructureSection> |
- | [[Category: Anderson | + | [[Category: Large Structures]] |
- | [[Category: Brunzelle | + | [[Category: Staphylococcus aureus subsp. aureus COL]] |
- | + | [[Category: Anderson WF]] | |
- | [[Category: Minasov | + | [[Category: Brunzelle J]] |
- | [[Category: Onopriyenko | + | [[Category: Minasov G]] |
- | [[Category: Peterson | + | [[Category: Onopriyenko O]] |
- | [[Category: Savchenko | + | [[Category: Peterson SN]] |
- | [[Category: Skarina | + | [[Category: Savchenko A]] |
- | + | [[Category: Skarina T]] | |
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Current revision
2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol
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