2wjf

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[[Image:2wjf.png|left|200px]]
 
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{{STRUCTURE_2wjf| PDB=2wjf | SCENE= }}
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==Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4 in complex with phosphate.==
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<StructureSection load='2wjf' size='340' side='right'caption='[[2wjf]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE CPS4B FROM STEPTOCOCCUS PNEUMONIAE TIGR4 IN COMPLEX WITH PHOSPHATE.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wjf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJF FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19616007}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjf OCA], [https://pdbe.org/2wjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjf RCSB], [https://www.ebi.ac.uk/pdbsum/2wjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjf ProSAT]</span></td></tr>
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[[2wjf]] is a 1 chain structure of [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJF OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPSB_STRPN CPSB_STRPN] Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wjf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wjf ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019616007</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
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[[Category: Hagelueken, G.]]
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[[Category: Hagelueken G]]
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[[Category: Huang, H.]]
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[[Category: Huang H]]
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[[Category: Naismith, J H.]]
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[[Category: Naismith JH]]
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[[Category: Capsule biogenesis/degradation]]
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[[Category: Exopolysaccharide synthesis]]
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[[Category: Hydrolase]]
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[[Category: Manganese]]
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[[Category: Phosphatase]]
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[[Category: Protein phosphatase]]
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Current revision

Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4 in complex with phosphate.

PDB ID 2wjf

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