1n8n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1n8n" [edit=sysop:move=sysop])
Current revision (07:54, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1n8n.png|left|200px]]
 
-
{{STRUCTURE_1n8n| PDB=1n8n | SCENE= }}
+
==Crystal structure of the Au3+ complex of AphA class B acid phosphatase/phosphotransferase from E. coli at 1.69 A resolution==
-
 
+
<StructureSection load='1n8n' size='340' side='right'caption='[[1n8n]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
-
===Crystal structure of the Au3+ complex of AphA class B acid phosphatase/phosphotransferase from E. coli at 1.69 A resolution===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1n8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N8N FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_14687572}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU3:GOLD+3++ION'>AU3</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n8n OCA], [https://pdbe.org/1n8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n8n RCSB], [https://www.ebi.ac.uk/pdbsum/1n8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n8n ProSAT]</span></td></tr>
-
[[1n8n]] is a 1 chain structure of [[Acid phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N8N OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/APHA_ECOLI APHA_ECOLI] Dephosphorylates several organic phosphate monoesters including 3'- and 5'-nucleotides, 2'-deoxy-5'-nucleotides, pNPP, phenyl phosphate, glycerol 2-phosphate, ribose 5-phosphate, O-phospho-L-amino acids and phytic acid, showing the highest activity with aryl phosphoesters (pNPP, phenyl phosphate and O-phospho-L-tyrosine), and to a lesser extent with 3'- and 5'-nucleotides. No activity toward ATP, phosphodiesters, glycerol-1-phosphate, glucose 1-phosphate, glucose 6-phosphate, NADP, GTP or 3',5'-cAMP, ADP or ATP. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds. Capable of transferring phosphate from either pNPP or UMP to adenosine or uridine. Does not exhibit nucleotide phosphomutase activity.<ref>PMID:9011040</ref> <ref>PMID:16297670</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/1n8n_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n8n ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Acid phosphatase|Acid phosphatase]]
+
*[[Acid phosphatase 3D structures|Acid phosphatase 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:014687572</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Acid phosphatase]]
+
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Benvenuti, M.]]
+
[[Category: Large Structures]]
-
[[Category: Calderone, V.]]
+
[[Category: Benvenuti M]]
-
[[Category: Forleo, C.]]
+
[[Category: Calderone V]]
-
[[Category: Mangani, S.]]
+
[[Category: Forleo C]]
-
[[Category: Rossolini, G M.]]
+
[[Category: Mangani S]]
-
[[Category: Thaller, M C.]]
+
[[Category: Rossolini GM]]
-
[[Category: Class b acid phosphatase]]
+
[[Category: Thaller MC]]
-
[[Category: Dddd acid phosphatase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Metallo-enzyme]]
+

Current revision

Crystal structure of the Au3+ complex of AphA class B acid phosphatase/phosphotransferase from E. coli at 1.69 A resolution

PDB ID 1n8n

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n8n"
Personal tools