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1dun

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[[Image:1dun.png|left|200px]]
 
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{{STRUCTURE_1dun| PDB=1dun | SCENE= }}
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==EIAV DUTPASE NATIVE==
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<StructureSection load='1dun' size='340' side='right'caption='[[1dun]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===EIAV DUTPASE NATIVE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DUN FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9878436}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dun OCA], [https://pdbe.org/1dun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dun RCSB], [https://www.ebi.ac.uk/pdbsum/1dun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dun ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1dun]] is a 1 chain structure of [[Deoxyuridine 5'-triphosphate nucleotidohydrolase]] with sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUN OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/POL_EIAV9 POL_EIAV9] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/1dun_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dun ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
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*[[DUTPase 3D structures|DUTPase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009878436</ref><ref group="xtra">PMID:011917145</ref><references group="xtra"/>
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[[Category: Equine infectious anemia virus]]
[[Category: Equine infectious anemia virus]]
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[[Category: DUTP diphosphatase]]
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[[Category: Large Structures]]
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[[Category: Cedergren-Zeppezauer, E S.]]
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[[Category: Cedergren-Zeppezauer ES]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter Z]]
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[[Category: Nyman, P O.]]
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[[Category: Nyman PO]]
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[[Category: Persson, R.]]
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[[Category: Persson R]]
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[[Category: Rosengren, A M.]]
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[[Category: Rosengren AM]]
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[[Category: Wilson, K S.]]
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[[Category: Wilson KS]]
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[[Category: Aspartyl protease]]
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[[Category: Dutpase]]
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[[Category: Eiav]]
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[[Category: Hydrolase]]
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[[Category: Trimeric enzyme]]
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Current revision

EIAV DUTPASE NATIVE

PDB ID 1dun

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