1g6r

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[[Image:1g6r.png|left|200px]]
 
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{{STRUCTURE_1g6r| PDB=1g6r | SCENE= }}
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==A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX==
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<StructureSection load='1g6r' size='340' side='right'caption='[[1g6r]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1g6r]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G6R FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10755612}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g6r OCA], [https://pdbe.org/1g6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g6r RCSB], [https://www.ebi.ac.uk/pdbsum/1g6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g6r ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1g6r]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6R OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/TVA1_MOUSE TVA1_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/1g6r_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g6r ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
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==Reference==
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*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
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<ref group="xtra">PMID:010755612</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Apostolopoulos, V.]]
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[[Category: Apostolopoulos V]]
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[[Category: Degano, M.]]
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[[Category: Degano M]]
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[[Category: Garcia, K C.]]
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[[Category: Garcia KC]]
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[[Category: Rudolph, M G.]]
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[[Category: Rudolph MG]]
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[[Category: Teyton, L.]]
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[[Category: Teyton L]]
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[[Category: Wilson, I A.]]
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[[Category: Wilson IA]]
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[[Category: Immune system]]
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[[Category: Major histocompatibility complex]]
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[[Category: Superagonist]]
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[[Category: T cell antigen receptor]]
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Current revision

A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX

PDB ID 1g6r

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