1zxv

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[[Image:1zxv.png|left|200px]]
 
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{{STRUCTURE_1zxv| PDB=1zxv | SCENE= }}
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==X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid.==
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<StructureSection load='1zxv' size='340' side='right'caption='[[1zxv]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
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===X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1zxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15983377}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MFM:(E)-3-(5((5-(4-CHLOROPHENYL)FURAN-2-YL)METHYLENE)-4-OXO-2-THIOXOTHIAZOLIDIN-3-YL)PROPANOIC+ACID'>MFM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxv OCA], [https://pdbe.org/1zxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxv RCSB], [https://www.ebi.ac.uk/pdbsum/1zxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxv ProSAT]</span></td></tr>
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[[1zxv]] is a 2 chain structure of [[Anthrax Lethal Factor]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q52NH3_BACAN Q52NH3_BACAN]
==See Also==
==See Also==
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*[[Anthrax Lethal Factor|Anthrax Lethal Factor]]
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*[[Anthrax lethal factor 3D structures|Anthrax lethal factor 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015983377</ref><references group="xtra"/>
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[[Category: Anthrax lethal factor endopeptidase]]
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[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Liddington, R C.]]
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[[Category: Large Structures]]
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[[Category: Wong, T Y.]]
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[[Category: Liddington RC]]
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[[Category: Anthrax toxin lethal factor]]
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[[Category: Wong TY]]
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[[Category: Hydrolase]]
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[[Category: Protein and small molecule inhibitor complex]]
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[[Category: Zinc metalloproteinase]]
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Current revision

X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid.

PDB ID 1zxv

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