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1u3e

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[[Image:1u3e.png|left|200px]]
 
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{{STRUCTURE_1u3e| PDB=1u3e | SCENE= }}
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==DNA binding and cleavage by the HNH homing endonuclease I-HmuI==
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<StructureSection load='1u3e' size='340' side='right'caption='[[1u3e]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
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===DNA binding and cleavage by the HNH homing endonuclease I-HmuI===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1u3e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_virus_SPO1 Bacillus virus SPO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U3E FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15313606}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3e OCA], [https://pdbe.org/1u3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3e RCSB], [https://www.ebi.ac.uk/pdbsum/1u3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3e ProSAT]</span></td></tr>
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[[1u3e]] is a 4 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_phage_spo1 Bacillus phage spo1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3E OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HMUI_BPSP1 HMUI_BPSP1]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u3/1u3e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u3e ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015313606</ref><references group="xtra"/>
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[[Category: Bacillus virus SPO1]]
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[[Category: Bacillus phage spo1]]
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[[Category: Large Structures]]
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[[Category: Landthaler, M.]]
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[[Category: Landthaler M]]
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[[Category: Shen, B W.]]
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[[Category: Shen BW]]
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[[Category: Shub, D A.]]
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[[Category: Shub DA]]
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[[Category: Stoddard, B L.]]
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[[Category: Stoddard BL]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Helix-turn-helix dna binding domain]]
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[[Category: Hnh catalytic motif]]
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[[Category: Protein-dna complex]]
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Current revision

DNA binding and cleavage by the HNH homing endonuclease I-HmuI

PDB ID 1u3e

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