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3q7a

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[[Image:3q7a.png|left|200px]]
 
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{{STRUCTURE_3q7a| PDB=3q7a | SCENE= }}
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==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123==
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<StructureSection load='3q7a' size='340' side='right'caption='[[3q7a]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7A FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21816822}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=778:4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE'>778</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7a OCA], [https://pdbe.org/3q7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7a RCSB], [https://www.ebi.ac.uk/pdbsum/3q7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7a ProSAT]</span></td></tr>
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[[3q7a]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Cryptococcus_neoformans Cryptococcus neoformans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7A OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q55S71_CRYNB Q55S71_CRYNB]
==See Also==
==See Also==
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*[[Farnesyltransferase|Farnesyltransferase]]
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*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021816822</ref><references group="xtra"/>
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[[Category: Cryptococcus neoformans var. grubii H99]]
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[[Category: Cryptococcus neoformans]]
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[[Category: Large Structures]]
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[[Category: Beese, L S.]]
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[[Category: Beese LS]]
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[[Category: Hast, M A.]]
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[[Category: Hast MA]]
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[[Category: Protein prenyltransferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123

PDB ID 3q7a

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