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1fzz

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[[Image:1fzz.png|left|200px]]
 
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{{STRUCTURE_1fzz| PDB=1fzz | SCENE= }}
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==THE CRYSTAL STRUCTURE OF THE COMPLEX OF NON-PEPTIDIC INHIBITOR ONO-6818 AND PORCINE PANCREATIC ELASTASE.==
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<StructureSection load='1fzz' size='340' side='right'caption='[[1fzz]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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===THE CRYSTAL STRUCTURE OF THE COMPLEX OF NON-PEPTIDIC INHIBITOR ONO-6818 AND PORCINE PANCREATIC ELASTASE.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fzz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FZZ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11310599}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=681:2-(5-AMINO-6-OXO-2-PHENYL-6H-PYRIMIDIN-1-YL)-N-[2-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-1-(METHYLETHYL)-2-HYDROXYETHYL]ACETAMIDE'>681</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fzz OCA], [https://pdbe.org/1fzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fzz RCSB], [https://www.ebi.ac.uk/pdbsum/1fzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fzz ProSAT]</span></td></tr>
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[[1fzz]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZZ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG] Acts upon elastin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fz/1fzz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fzz ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Elastase|Elastase]]
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*[[Elastase 3D structures|Elastase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011310599</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Pancreatic elastase]]
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[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Hamanaka, N.]]
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[[Category: Hamanaka N]]
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[[Category: Katsuya, Y.]]
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[[Category: Katsuya Y]]
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[[Category: Matsuoka, S.]]
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[[Category: Matsuoka S]]
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[[Category: Nakai, H.]]
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[[Category: Nakai H]]
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[[Category: Odagaki, Y.]]
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[[Category: Odagaki Y]]
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[[Category: Ohmoto, K.]]
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[[Category: Ohmoto K]]
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[[Category: Toda, M.]]
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[[Category: Toda M]]
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[[Category: Enzyme-inhibitor complex]]
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[[Category: Hydrolase]]
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Current revision

THE CRYSTAL STRUCTURE OF THE COMPLEX OF NON-PEPTIDIC INHIBITOR ONO-6818 AND PORCINE PANCREATIC ELASTASE.

PDB ID 1fzz

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