2vk4

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[[Image:2vk4.png|left|200px]]
 
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{{STRUCTURE_2vk4| PDB=2vk4 | SCENE= }}
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==Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis==
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<StructureSection load='2vk4' size='340' side='right'caption='[[2vk4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF PYRUVATE DECARBOXYLASE FROM KLUYVEROMYCES LACTIS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2vk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g1i 2g1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VK4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16939618}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vk4 OCA], [https://pdbe.org/2vk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2vk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vk4 ProSAT]</span></td></tr>
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[[2vk4]] is a 4 chain structure of [[Pyruvate decarboxylase]] with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g1i 2g1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDC1_KLULA PDC1_KLULA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vk4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vk4 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016939618</ref><references group="xtra"/>
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[[Category: Kluyveromyces lactis]]
[[Category: Kluyveromyces lactis]]
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[[Category: Pyruvate decarboxylase]]
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[[Category: Large Structures]]
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[[Category: Konig, S.]]
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[[Category: Konig S]]
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[[Category: Kutter, S.]]
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[[Category: Kutter S]]
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[[Category: Relle, S.]]
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[[Category: Relle S]]
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[[Category: Weiss, M S.]]
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[[Category: Weiss MS]]
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[[Category: Wille, G.]]
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[[Category: Wille G]]
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[[Category: Asymmetric active site]]
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[[Category: Decarboxylase]]
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[[Category: Dimer of dimer]]
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[[Category: Flavoprotein]]
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[[Category: Lyase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Substrate activation]]
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[[Category: Tdp]]
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[[Category: Thiamine diphosphate]]
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[[Category: Thiamine pyrophosphate]]
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[[Category: Tpp]]
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Current revision

Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis

PDB ID 2vk4

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