1qks

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[[Image:1qks.png|left|200px]]
 
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{{STRUCTURE_1qks| PDB=1qks | SCENE= }}
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==CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM==
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<StructureSection load='1qks' size='340' side='right'caption='[[1qks]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paracoccus_pantotrophus Paracoccus pantotrophus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QKS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qks OCA], [https://pdbe.org/1qks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qks RCSB], [https://www.ebi.ac.uk/pdbsum/1qks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qks ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NIRS_PARPN NIRS_PARPN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/1qks_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qks ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Cytochrome cd1-nitrite reductase is a bifunctional enzyme that catalyzes the one-electron reduction of nitrite to nitric oxide and the four-electron reduction of oxygen to water. The 1.55 A crystal structure of the dimeric enzyme from Thiosphaera pantotropha is reported here. The protein was sequenced from the X-ray structure. Each subunit contains a covalent c heme with two axial His ligands (His-17, His-69) and a unique noncovalent d1 heme ligated by Tyr-25 and His-200. The d1 heme is the mononuclear iron center where both oxygen and nitrite reduction take place. The two types of heme are located in separate domains whose arrangement suggests a mechanism requiring domain movement during catalysis.
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===CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM===
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The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1.,Fulop V, Moir JW, Ferguson SJ, Hajdu J Cell. 1995 May 5;81(3):369-77. PMID:7736589<ref>PMID:7736589</ref>
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{{ABSTRACT_PUBMED_7736589}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1qks" style="background-color:#fffaf0;"></div>
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[[1qks]] is a 2 chain structure of [[Cytochrome c]] and [[Nitric reductase]] with sequence from [http://en.wikipedia.org/wiki/Paracoccus_pantotrophus Paracoccus pantotrophus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA].
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==See Also==
==See Also==
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*[[Cytochrome c|Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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*[[Nitric reductase|Nitric reductase]]
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*[[Cytochrome c nitrite reductase|Cytochrome c nitrite reductase]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:007736589</ref><ref group="xtra">PMID:009199411</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Paracoccus pantotrophus]]
[[Category: Paracoccus pantotrophus]]
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[[Category: Fulop, V.]]
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[[Category: Fulop V]]
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[[Category: Denitrification]]
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[[Category: Electron transport]]
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[[Category: Enzyme]]
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[[Category: Nitrite reductase]]
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[[Category: Oxidoreductase]]
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[[Category: Periplasmic]]
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Current revision

CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM

PDB ID 1qks

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