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1jh7

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[[Image:1jh7.png|left|200px]]
 
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{{STRUCTURE_1jh7| PDB=1jh7 | SCENE= }}
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==Semi-reduced Inhibitor-bound Cyclic Nucleotide Phosphodiesterase from Arabidopsis thaliana==
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<StructureSection load='1jh7' size='340' side='right'caption='[[1jh7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===Semi-reduced Inhibitor-bound Cyclic Nucleotide Phosphodiesterase from Arabidopsis thaliana===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jh7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JH7 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11694509}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UVC:URIDINE-2,3-VANADATE'>UVC</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jh7 OCA], [https://pdbe.org/1jh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jh7 RCSB], [https://www.ebi.ac.uk/pdbsum/1jh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jh7 ProSAT]</span></td></tr>
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[[1jh7]] is a 1 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JH7 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPD_ARATH CPD_ARATH] Hydrolyzes ADP-ribose 1",2"-cyclic phosphate (Appr>1) that is produced during tRNA splicing into ADP-ribose 1"-phosphate (Appr-1"p). Acts also on nucleoside 2',3'-cyclic phosphates.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jh/1jh7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jh7 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphodiesterase|Phosphodiesterase]]
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011694509</ref><references group="xtra"/>
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Botos, I.]]
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[[Category: Large Structures]]
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[[Category: Filipowicz, W.]]
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[[Category: Botos I]]
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[[Category: Grella, M.]]
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[[Category: Filipowicz W]]
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[[Category: Hofmann, A.]]
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[[Category: Grella M]]
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[[Category: Wlodawer, A.]]
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[[Category: Hofmann A]]
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[[Category: 2s']]
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[[Category: Wlodawer A]]
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[[Category: 2''-cyclic phosphate]]
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[[Category: 3'-cyclic nucleotide phosphodiesterase]]
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[[Category: 3'-cyclic uridine vanadate]]
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[[Category: Adp-ribose 1's']]
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[[Category: Hydrolase]]
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[[Category: Rna processing]]
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Current revision

Semi-reduced Inhibitor-bound Cyclic Nucleotide Phosphodiesterase from Arabidopsis thaliana

PDB ID 1jh7

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