3enj

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[[Image:3enj.png|left|200px]]
 
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{{STRUCTURE_3enj| PDB=3enj | SCENE= }}
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==Structure of Pig Heart Citrate Synthase at 1.78 A resolution==
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<StructureSection load='3enj' size='340' side='right'caption='[[3enj]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3enj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ENJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3enj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3enj OCA], [https://pdbe.org/3enj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3enj RCSB], [https://www.ebi.ac.uk/pdbsum/3enj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3enj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CISY_PIG CISY_PIG]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/3enj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3enj ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Pig heart citrate synthase was crystallized from a small-molecule cocktail containing cystamine dihydrochloride, aspartame and benzamidine hydrochloride. The structure was refined to an R factor of 0.179 (R(free) = 0.222) using synchrotron data to a resolution of 1.78 A. The model includes the full-length protein, a chloride ion, a sulfate ion, 305 water molecules and an unexpected moiety attached through a disulfide linkage to Cys184, which was modeled as a half-cystamine molecule generated by disulfide exchange with the cystamine in the small-molecule cocktail.
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===Structure of Pig Heart Citrate Synthase at 1.78 A resolution===
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Structure of pig heart citrate synthase at 1.78 A resolution.,Larson SB, Day JS, Nguyen C, Cudney R, McPherson A Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt, 5):430-4. Epub 2009 Apr 24. PMID:19407370<ref>PMID:19407370</ref>
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{{ABSTRACT_PUBMED_19407370}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 3enj" style="background-color:#fffaf0;"></div>
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[[3enj]] is a 1 chain structure of [[Citrate Synthase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENJ OCA].
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==See Also==
==See Also==
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*[[Citrate Synthase|Citrate Synthase]]
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*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:019407370</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: CHTSB, Center for High-Throughput Structural Biology.]]
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[[Category: Cudney R]]
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[[Category: Cudney, R.]]
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[[Category: Day JS]]
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[[Category: Day, J S.]]
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[[Category: Larson SB]]
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[[Category: Larson, S B.]]
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[[Category: McPherson A]]
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[[Category: McPherson, A.]]
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[[Category: Nguyen C]]
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[[Category: Nguyen, C.]]
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[[Category: Center for high-throughput structural biology]]
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[[Category: Chtsb]]
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[[Category: Disulfide exchange]]
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[[Category: Lyase]]
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[[Category: Methylation]]
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[[Category: Mitochondrion]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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[[Category: Transit peptide]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Structure of Pig Heart Citrate Synthase at 1.78 A resolution

PDB ID 3enj

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