1evb
From Proteopedia
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| - | [[Image:1evb.jpg|left|200px]]<br /><applet load="1evb" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1evb" /> | ||
| - | '''Cyanobacterial toxin, phosphatase-1/-2A inhibitor, NMR'''<br /> | ||
| - | == | + | ==NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor== |
| + | <StructureSection load='1evb' size='340' side='right'caption='[[1evb]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1evb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Microcystis Microcystis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1ZN:(2S,3S,4E,6E,8S,9S)-3-AMINO-9-METHOXY-2,6,8-TRIMETHYL-10-PHENYLDECA-4,6-DIENOIC+ACID'>1ZN</scene>, <scene name='pdbligand=ACB:3-METHYL-BETA-D-ASPARTIC+ACID'>ACB</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAM:N-METHYL-ALPHA-BETA-DEHYDROALANINE'>DAM</scene>, <scene name='pdbligand=FGA:GAMMA-D-GLUTAMIC+ACID'>FGA</scene>, <scene name='pdbligand=PRD_000212:Microcystin+LR'>PRD_000212</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evb OCA], [https://pdbe.org/1evb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evb RCSB], [https://www.ebi.ac.uk/pdbsum/1evb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets. | A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets. | ||
| - | + | Comparison of the solution structures of microcystin-LR and motuporin.,Bagu JR, Sonnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF Nat Struct Biol. 1995 Feb;2(2):114-6. PMID:7749913<ref>PMID:7749913</ref> | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 1evb" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Microcystis]] | [[Category: Microcystis]] | ||
| - | + | [[Category: Bagu JR]] | |
| - | [[Category: Bagu | + | [[Category: Sykes BD]] |
| - | [[Category: Sykes | + | |
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Current revision
NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor
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