3ie2
From Proteopedia
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| - | [[Image:3ie2.png|left|200px]] | ||
| - | + | ==Crystal Structure of H400V mutant TTHA0252 from Thermus thermophilus HB8== | |
| - | + | <StructureSection load='3ie2' size='340' side='right'caption='[[3ie2]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ie2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2yvd 2yvd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IE2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[3ie2]] is a 4 chain structure | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ie2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ie2 OCA], [https://pdbe.org/3ie2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ie2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ie2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ie2 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNSE_THET8 RNSE_THET8] Has endoribonuclease activity towards 23S and 16S rRNA (in vitro). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ie2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ie2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Ribonuclease|Ribonuclease]] | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
| - | [[Category: Thermus thermophilus]] | + | __TOC__ |
| - | [[Category: Ishikawa | + | </StructureSection> |
| - | [[Category: Kuramitsu | + | [[Category: Large Structures]] |
| - | [[Category: Masui | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: Nakagawa | + | [[Category: Ishikawa H]] |
| - | + | [[Category: Kuramitsu S]] | |
| - | [[Category: Yokoyama | + | [[Category: Masui R]] |
| - | + | [[Category: Nakagawa N]] | |
| - | + | [[Category: Yokoyama S]] | |
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Current revision
Crystal Structure of H400V mutant TTHA0252 from Thermus thermophilus HB8
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