1cxc

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[[Image:1cxc.png|left|200px]]
 
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{{STRUCTURE_1cxc| PDB=1cxc | SCENE= }}
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==CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS==
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<StructureSection load='1cxc' size='340' side='right'caption='[[1cxc]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1cxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides Cereibacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CXC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxc OCA], [https://pdbe.org/1cxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cxc RCSB], [https://www.ebi.ac.uk/pdbsum/1cxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cxc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYC2_CERSP CYC2_CERSP] Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/1cxc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cxc ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Cytochrome c(2) serves as the secondary electron donor that reduces the photo-oxidized bacteriochlorophyll dimer in photosynthetic bacteria. Cytochrome c(2) from Rhodobacter sphaeroides has been crystallized in three different forms. At high ionic strength, crystals of a hexagonal space group (P6(1)22) were obtained, while at low ionic strength, triclinic (P1) and tetragonal (P4(1)2(1)2) crystals were formed. The three-dimensional structures of the cytochrome in all three crystal forms have been determined by X-ray diffraction at resolutions of 2.20 A (hexagonal), 1.95 A, (triclinic) and 1.53 A (tetragonal). The most significant difference observed was the binding of an imidazole molecule to the iron atom of the heme group in the hexagonal structure. This binding displaces the sulfur atom of Met l00, which forms the axial ligand in the triclinic and tetragonal structures.
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===CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS===
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Crystallization and X-ray structure determination of cytochrome c2 from Rhodobacter sphaeroides in three crystal forms.,Axelrod HL, Feher G, Allen JP, Chirino AJ, Day MW, Hsu BT, Rees DC Acta Crystallogr D Biol Crystallogr. 1994 Jul 1;50(Pt 4):596-602. PMID:15299423<ref>PMID:15299423</ref>
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{{ABSTRACT_PUBMED_15299423}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1cxc" style="background-color:#fffaf0;"></div>
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[[1cxc]] is a 1 chain structure of [[Cytochrome c]] with sequence from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXC OCA].
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==See Also==
==See Also==
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*[[Cytochrome c|Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:015299423</ref><ref group="xtra">PMID:012051924</ref><references group="xtra"/>
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__TOC__
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[[Category: Rhodobacter sphaeroides]]
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</StructureSection>
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[[Category: Allen, J P.]]
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[[Category: Cereibacter sphaeroides]]
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[[Category: Axelrod, H L.]]
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[[Category: Large Structures]]
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[[Category: Chirino, A J.]]
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[[Category: Allen JP]]
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[[Category: Day, M W.]]
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[[Category: Axelrod HL]]
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[[Category: Feher, G.]]
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[[Category: Chirino AJ]]
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[[Category: Hsu, B T.]]
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[[Category: Day MW]]
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[[Category: Rees, D C.]]
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[[Category: Feher G]]
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[[Category: Hsu BT]]
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[[Category: Rees DC]]

Current revision

CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS

PDB ID 1cxc

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