This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3no9
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3no9.png|left|200px]] | ||
| - | + | ==Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis== | |
| - | + | <StructureSection load='3no9' size='340' side='right'caption='[[3no9]], [[Resolution|resolution]] 2.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3no9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NO9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48Å</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3no9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no9 OCA], [https://pdbe.org/3no9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3no9 RCSB], [https://www.ebi.ac.uk/pdbsum/3no9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3no9 ProSAT]</span></td></tr> |
| - | [[3no9]] is a 4 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FUMC_MYCTU FUMC_MYCTU] Catalyzes the reversible addition of water to fumarate to give L-malate. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/3no9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3no9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Fumarase|Fumarase]] | *[[Fumarase|Fumarase]] | ||
| - | [[Category: | + | __TOC__ |
| - | [[Category: Mycobacterium tuberculosis]] | + | </StructureSection> |
| - | [[Category: Hung | + | [[Category: Large Structures]] |
| - | [[Category: Li | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Sacchettini | + | [[Category: Hung L-W]] |
| - | [[Category: Swanson | + | [[Category: Li H]] |
| - | + | [[Category: Sacchettini JC]] | |
| - | [[Category: Yu | + | [[Category: Swanson S]] |
| - | + | [[Category: Yu M]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
| |||||||||||

