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3qw0
From Proteopedia
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| - | [[Image:3qw0.png|left|200px]] | ||
| - | + | ==Crystal structure of the Zn-RIDC1 complex stabilized by BMB crosslinks== | |
| + | <StructureSection load='3qw0' size='340' side='right'caption='[[3qw0]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3qw0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QW0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ME9:1,1-BUTANE-1,4-DIYLBIS(1H-PYRROLE-2,5-DIONE)'>ME9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qvy|3qvy]], [[3qvz|3qvz]], [[3qw1|3qw1]], [[3hni|3hni]], [[3iq6|3iq6]]</div></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qw0 OCA], [https://pdbe.org/3qw0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qw0 RCSB], [https://www.ebi.ac.uk/pdbsum/3qw0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qw0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Here, we report that the approach of metal-templated ligand synthesis can be applied to construct a dimeric protein assembly ((BMOE)RIDC1(2)), which is stabilized by noncovalent interactions and flexible covalent cross-linkers around the Zn templates. Despite its flexibility, (BMOE)RIDC1(2) selectively binds Zn(II) over other divalent metals and undergoes dimerization upon metal binding. Such simultaneous fulfillment of plasticity and selectivity is a hallmark of cellular signaling events that involve ligand/metal-induced protein dimerization. | ||
| - | + | Templated Construction of a Zn-Selective Protein Dimerization Motif.,Salgado EN, Brodin JD, To MM, Tezcan FA Inorg Chem. 2011 Jun 7. PMID:21648390<ref>PMID:21648390</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 3qw0" style="background-color:#fffaf0;"></div> | |
| - | + | ||
==See Also== | ==See Also== | ||
| - | *[[Cytochrome | + | *[[Cytochrome C 3D structures|Cytochrome C 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Salgado, E N | + | [[Category: Bacillus coli migula 1895]] |
| - | [[Category: Tezcan, F A | + | [[Category: Large Structures]] |
| + | [[Category: Salgado, E N]] | ||
| + | [[Category: Tezcan, F A]] | ||
[[Category: Four-helix bundle]] | [[Category: Four-helix bundle]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Current revision
Crystal structure of the Zn-RIDC1 complex stabilized by BMB crosslinks
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