2g3y

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[[Image:2g3y.png|left|200px]]
 
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{{STRUCTURE_2g3y| PDB=2g3y | SCENE= }}
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==Crystal structure of the human small GTPase GEM==
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<StructureSection load='2g3y' size='340' side='right'caption='[[2g3y]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===Crystal structure of the human small GTPase GEM===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2g3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3Y FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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[[2g3y]] is a 1 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3y OCA], [https://pdbe.org/2g3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3y RCSB], [https://www.ebi.ac.uk/pdbsum/2g3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3y ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GEM_HUMAN GEM_HUMAN] Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3y ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[GTP-binding protein|GTP-binding protein]]
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Berridge, G.]]
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[[Category: Arrowsmith C]]
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[[Category: Bray, J.]]
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[[Category: Berridge G]]
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[[Category: Burgess, N.]]
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[[Category: Bray J]]
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[[Category: Delft, F von.]]
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[[Category: Burgess N]]
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[[Category: Doyle, D.]]
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[[Category: Doyle D]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Elkins, J.]]
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[[Category: Elkins J]]
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[[Category: Fedorov, O.]]
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[[Category: Fedorov O]]
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[[Category: Gileadi, C.]]
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[[Category: Gileadi C]]
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[[Category: Lee, W H.]]
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[[Category: Lee WH]]
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[[Category: Pantic, N.]]
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[[Category: Pantic N]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Schoch G]]
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[[Category: Schoch, G.]]
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[[Category: Sobott F]]
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[[Category: Sobott, F.]]
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[[Category: Soundararajan M]]
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[[Category: Soundararajan, M.]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M.]]
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[[Category: Turnbull A]]
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[[Category: Turnbull, A.]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Von Delft F]]
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[[Category: Gdp]]
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[[Category: Gem]]
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[[Category: Inactive state]]
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[[Category: Rgk family]]
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[[Category: Sgc]]
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[[Category: Signaling protein]]
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[[Category: Small gtpase]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of the human small GTPase GEM

PDB ID 2g3y

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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