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1ako
From Proteopedia
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| - | [[Image:1ako.png|left|200px]] | ||
| - | + | ==EXONUCLEASE III FROM ESCHERICHIA COLI== | |
| - | + | <StructureSection load='1ako' size='340' side='right'caption='[[1ako]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ako]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AKO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ako FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ako OCA], [https://pdbe.org/1ako PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ako RCSB], [https://www.ebi.ac.uk/pdbsum/1ako PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ako ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1ako]] | + | == Function == |
| + | [https://www.uniprot.org/uniprot/EX3_ECOLI EX3_ECOLI] Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease, 3'-phosphomonoesterase, 3'-repair diesterase and ribonuclease H activities. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ak/1ako_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ako ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Endonuclease|Endonuclease]] | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] |
| - | *[[Exonuclease|Exonuclease]] | + | *[[Exonuclease 3D structures|Exonuclease 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Escherichia coli K-12]] | |
| - | [[Category: Escherichia coli]] | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Cunningham RP]] |
| - | [[Category: Cunningham | + | [[Category: Kuo C-F]] |
| - | [[Category: Kuo | + | [[Category: Mol CD]] |
| - | [[Category: Mol | + | [[Category: Tainer JA]] |
| - | [[Category: Tainer | + | [[Category: Thayer MM]] |
| - | [[Category: Thayer | + | |
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Current revision
EXONUCLEASE III FROM ESCHERICHIA COLI
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