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3hzq
From Proteopedia
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| - | [[Image:3hzq.png|left|200px]] | ||
| - | + | ==Structure of a tetrameric MscL in an expanded intermediate state== | |
| - | + | <StructureSection load='3hzq' size='340' side='right'caption='[[3hzq]], [[Resolution|resolution]] 3.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3hzq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.82Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzq OCA], [https://pdbe.org/3hzq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzq RCSB], [https://www.ebi.ac.uk/pdbsum/3hzq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzq ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3hzq]] | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MSCL_STAAW MSCL_STAAW] Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzq_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hzq ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Ion channels|Ion channels]] | + | *[[Ion channels 3D structures|Ion channels 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Staphylococcus aureus subsp. aureus MW2]] | |
| - | [[Category: Staphylococcus aureus subsp. aureus | + | [[Category: Gandhi CS]] |
| - | [[Category: Gandhi | + | [[Category: Liu ZF]] |
| - | [[Category: Liu | + | [[Category: Rees DC]] |
| - | [[Category: Rees | + | |
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Current revision
Structure of a tetrameric MscL in an expanded intermediate state
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