3rjm

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[[Image:3rjm.png|left|200px]]
 
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{{STRUCTURE_3rjm| PDB=3rjm | SCENE= }}
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==CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c==
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<StructureSection load='3rjm' size='340' side='right'caption='[[3rjm]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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===CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rjm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21903398}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PX:(3S)-3-(PROPAN-2-YLOXY)-L-PROLINE'>3PX</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASJ:(3S)-3-AMINO-4-HYDROXYBUTANOIC+ACID'>ASJ</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjm OCA], [https://pdbe.org/3rjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjm RCSB], [https://www.ebi.ac.uk/pdbsum/3rjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjm ProSAT]</span></td></tr>
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[[3rjm]] is a 6 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJM OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CASP2_HUMAN CASP2_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
==See Also==
==See Also==
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*[[Caspase|Caspase]]
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*[[Caspase 3D structures|Caspase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021903398</ref><references group="xtra"/>
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[[Category: Caspase-2]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Abendroth, J.]]
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[[Category: Large Structures]]
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[[Category: Kiselyov, A S.]]
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[[Category: Abendroth J]]
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[[Category: Lorimer, D.]]
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[[Category: Kiselyov AS]]
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[[Category: Maillard, M.]]
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[[Category: Lorimer D]]
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[[Category: Stewart, L.]]
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[[Category: Maillard M]]
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[[Category: Caspase]]
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[[Category: Stewart L]]
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[[Category: Caspase-2]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: P12]]
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[[Category: P19]]
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Current revision

CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c

PDB ID 3rjm

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