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1hwy

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[[Image:1hwy.png|left|200px]]
 
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{{STRUCTURE_1hwy| PDB=1hwy | SCENE= }}
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==BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE==
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<StructureSection load='1hwy' size='340' side='right'caption='[[1hwy]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1hwy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HWY FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11254391}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hwy OCA], [https://pdbe.org/1hwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hwy RCSB], [https://www.ebi.ac.uk/pdbsum/1hwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hwy ProSAT]</span></td></tr>
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[[1hwy]] is a 6 chain structure of [[Glutamate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWY OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHE3_BOVIN DHE3_BOVIN] May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).<ref>PMID:14659072</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/1hwy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hwy ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Glutamate dehydrogenase|Glutamate dehydrogenase]]
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*[[Glutamate dehydrogenase 3D structures|Glutamate dehydrogenase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011254391</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Fang, J.]]
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[[Category: Large Structures]]
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[[Category: Peterson, P E.]]
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[[Category: Fang J]]
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[[Category: Schmidt, T.]]
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[[Category: Peterson PE]]
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[[Category: Smith, T J.]]
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[[Category: Schmidt T]]
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[[Category: Stanley, C A.]]
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[[Category: Smith TJ]]
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[[Category: Allostery]]
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[[Category: Stanley CA]]
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[[Category: Glutamate dehydrogenase]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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Current revision

BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE

PDB ID 1hwy

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