3sb5

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[[Image:3sb5.png|left|200px]]
 
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{{STRUCTURE_3sb5| PDB=3sb5 | SCENE= }}
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==Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization==
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<StructureSection load='3sb5' size='340' side='right'caption='[[3sb5]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
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===Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sb5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SB5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21898649}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.46&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sb5 OCA], [https://pdbe.org/3sb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sb5 RCSB], [https://www.ebi.ac.uk/pdbsum/3sb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sb5 ProSAT]</span></td></tr>
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[[3sb5]] is a 4 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SB5 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
==See Also==
==See Also==
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*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021898649</ref><references group="xtra"/>
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__TOC__
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[[Category: Enterobacteria phage t4]]
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</StructureSection>
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[[Category: Lysozyme]]
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[[Category: Escherichia virus T4]]
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[[Category: Cascio, D.]]
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[[Category: Large Structures]]
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[[Category: Laganowsky, A.]]
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[[Category: Cascio D]]
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[[Category: Sawaya, M R.]]
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[[Category: Laganowsky A]]
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[[Category: Soriaga, A B.]]
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[[Category: Sawaya MR]]
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[[Category: Yeates, T O.]]
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[[Category: Soriaga AB]]
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[[Category: Zhao, M.]]
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[[Category: Yeates TO]]
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[[Category: Hydrolase]]
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[[Category: Zhao M]]
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[[Category: Metal-mediated synthetic symmetrization]]
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[[Category: Synthetic symmetrization]]
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Current revision

Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization

PDB ID 3sb5

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