This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2rkc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2rkc" [edit=sysop:move=sysop])
Current revision (13:11, 26 July 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2rkc.png|left|200px]]
 
-
{{STRUCTURE_2rkc| PDB=2rkc | SCENE= }}
+
==Crystal structure of the measles virus hemagglutinin==
-
 
+
<StructureSection load='2rkc' size='340' side='right'caption='[[2rkc]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
===Crystal structure of the measles virus hemagglutinin===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2rkc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Measles_morbillivirus Measles morbillivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RKC FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_018026116}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rkc OCA], [https://pdbe.org/2rkc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rkc RCSB], [https://www.ebi.ac.uk/pdbsum/2rkc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rkc ProSAT]</span></td></tr>
-
[[2rkc]] is a 1 chain structure of [[Hemagglutinin]] with sequence from [http://en.wikipedia.org/wiki/Measles_virus Measles virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKC OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HEMA_MEASE HEMA_MEASE] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis.<ref>PMID:9811778</ref>
==See Also==
==See Also==
-
*[[Hemagglutinin|Hemagglutinin]]
+
*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:018026116</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Measles virus]]
+
</StructureSection>
-
[[Category: Colf, L A.]]
+
[[Category: Large Structures]]
-
[[Category: Garcia, K C.]]
+
[[Category: Measles morbillivirus]]
-
[[Category: Juo, Z S.]]
+
[[Category: Colf LA]]
-
[[Category: Envelope protein]]
+
[[Category: Garcia KC]]
-
[[Category: Hemagglutinin]]
+
[[Category: Juo ZS]]
-
[[Category: Measles virus]]
+
-
[[Category: Membrane]]
+
-
[[Category: Transmembrane]]
+
-
[[Category: Viral protein]]
+
-
[[Category: Virion]]
+

Current revision

Crystal structure of the measles virus hemagglutinin

PDB ID 2rkc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2rkc"
Personal tools