2nuz
From Proteopedia
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| - | [[Image:2nuz.png|left|200px]] | ||
| - | + | ==crystal structure of alpha spectrin SH3 domain measured at room temperature== | |
| - | + | <StructureSection load='2nuz' size='340' side='right'caption='[[2nuz]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2nuz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NUZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nuz OCA], [https://pdbe.org/2nuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nuz RCSB], [https://www.ebi.ac.uk/pdbsum/2nuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nuz ProSAT]</span></td></tr> |
| - | [[2nuz]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nuz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nuz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Spectrin|Spectrin]] | + | *[[Spectrin 3D structures|Spectrin 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Agarwal | + | [[Category: Large Structures]] |
| - | [[Category: Chevelkov | + | [[Category: Agarwal V]] |
| - | [[Category: Diehl | + | [[Category: Chevelkov V]] |
| - | [[Category: Faelber | + | [[Category: Diehl A]] |
| - | [[Category: Hologne | + | [[Category: Faelber K]] |
| - | [[Category: Oschkinat | + | [[Category: Hologne M]] |
| - | [[Category: Reif | + | [[Category: Oschkinat H]] |
| - | + | [[Category: Reif B]] | |
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Current revision
crystal structure of alpha spectrin SH3 domain measured at room temperature
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Categories: Gallus gallus | Large Structures | Agarwal V | Chevelkov V | Diehl A | Faelber K | Hologne M | Oschkinat H | Reif B
