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3dhw

From Proteopedia

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[[Image:3dhw.png|left|200px]]
 
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{{STRUCTURE_3dhw| PDB=3dhw | SCENE= }}
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==Crystal structure of methionine importer MetNI==
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<StructureSection load='3dhw' size='340' side='right'caption='[[3dhw]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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===Crystal structure of methionine importer MetNI===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3dhw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18621668}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dhw OCA], [https://pdbe.org/3dhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dhw RCSB], [https://www.ebi.ac.uk/pdbsum/3dhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dhw ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3dhw]] is a 8 chain structure of [[ABC transporter]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHW OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/METI_ECOLI METI_ECOLI] Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/3dhw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dhw ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ABC transporter|ABC transporter]]
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:018621668</ref><references group="xtra"/>
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Johnson, E.]]
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[[Category: Johnson E]]
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[[Category: Kadaba, N S.]]
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[[Category: Kadaba NS]]
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[[Category: Kaiser, J T.]]
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[[Category: Kaiser JT]]
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[[Category: Lee, A T.]]
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[[Category: Lee AT]]
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[[Category: Rees, D C.]]
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[[Category: Rees DC]]
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[[Category: Abc-transporter]]
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[[Category: Amino-acid transport]]
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[[Category: Atp-binding]]
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[[Category: Hydrolase]]
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[[Category: Inner membrane]]
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[[Category: Membrane protein]]
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[[Category: Membrane protein-hydrolase complex]]
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[[Category: Methionine uptake transporter]]
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[[Category: Nucleotide-binding]]
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[[Category: Transmembrane]]
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Current revision

Crystal structure of methionine importer MetNI

PDB ID 3dhw

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