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1md2
From Proteopedia
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| - | [[Image:1md2.png|left|200px]] | ||
| - | + | ==CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013== | |
| - | + | <StructureSection load='1md2' size='340' side='right'caption='[[1md2]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1md2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MD2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=233:[5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLCARBAMOYL)-PENTYL]-CARBAMIC+ACID+METHYL+ESTER'>233</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=SQ:3-ETHYLAMINO-4-METHYLAMINO-CYCLOBUTANE-1,2-DIONE'>SQ</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1md2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md2 OCA], [https://pdbe.org/1md2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1md2 RCSB], [https://www.ebi.ac.uk/pdbsum/1md2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1md2 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1md2]] | + | == Function == |
| + | [[https://www.uniprot.org/uniprot/CHTB_VIBCH CHTB_VIBCH]] The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself. | ||
==See Also== | ==See Also== | ||
| - | *[[Cholera toxin|Cholera toxin]] | + | *[[Cholera toxin 3D structures|Cholera toxin 3D structures]] |
*[[User:David Solfiell/sandbox 1|User:David Solfiell/sandbox 1]] | *[[User:David Solfiell/sandbox 1|User:David Solfiell/sandbox 1]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Vibrio cholerae]] | [[Category: Vibrio cholerae]] | ||
| - | [[Category: Ahn | + | [[Category: Ahn M]] |
| - | [[Category: Fan | + | [[Category: Fan E]] |
| - | [[Category: Hol | + | [[Category: Hol WGJ]] |
| - | [[Category: Merritt | + | [[Category: Merritt EA]] |
| - | [[Category: Roach | + | [[Category: Roach C]] |
| - | [[Category: Zhang | + | [[Category: Zhang Z]] |
| - | + | ||
| - | + | ||
Current revision
CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013
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Categories: Large Structures | Vibrio cholerae | Ahn M | Fan E | Hol WGJ | Merritt EA | Roach C | Zhang Z
