2k3k
From Proteopedia
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| - | [[Image:2k3k.png|left|200px]] | ||
| - | + | ==Solution structure of Drosophila melanogaster SNF RBD1== | |
| - | + | <StructureSection load='2k3k' size='340' side='right'caption='[[2k3k]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr> |
| - | [[2k3k]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/2k3k_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k3k ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Nucleoprotein|Nucleoprotein]] | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Cui | + | [[Category: Large Structures]] |
| - | [[Category: Hu | + | [[Category: Cui G]] |
| - | [[Category: Jin | + | [[Category: Hu J]] |
| - | [[Category: Liu | + | [[Category: Jin C]] |
| - | [[Category: Xia | + | [[Category: Liu C]] |
| - | + | [[Category: Xia B]] | |
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Current revision
Solution structure of Drosophila melanogaster SNF RBD1
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Categories: Drosophila melanogaster | Large Structures | Cui G | Hu J | Jin C | Liu C | Xia B
