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1ith

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[[Image:1ith.png|left|200px]]
 
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{{STRUCTURE_1ith| PDB=1ith | SCENE= }}
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==STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION==
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<StructureSection load='1ith' size='340' side='right'caption='[[1ith]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ith]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Urechis_caupo Urechis caupo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ITH FirstGlance]. <br>
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{{ABSTRACT_PUBMED_1515107}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ith OCA], [https://pdbe.org/1ith PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ith RCSB], [https://www.ebi.ac.uk/pdbsum/1ith PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ith ProSAT]</span></td></tr>
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[[1ith]] is a 2 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Urechis_caupo Urechis caupo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITH OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HBF1_URECA HBF1_URECA] Hemoglobin F-I appears to function in storage, rather than transport of oxygen.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/1ith_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ith ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hemoglobin|Hemoglobin]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:001515107</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Urechis caupo]]
[[Category: Urechis caupo]]
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[[Category: Ernst, S R.]]
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[[Category: Ernst SR]]
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[[Category: Hackert, M.]]
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[[Category: Hackert M]]
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[[Category: Hendrickson, W A.]]
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[[Category: Hendrickson WA]]
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[[Category: Kolatkar, P.]]
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[[Category: Kolatkar P]]
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[[Category: Merritt, E A.]]
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[[Category: Merritt EA]]
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[[Category: Ogata, C M.]]
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[[Category: Ogata CM]]
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[[Category: Phizackerley, R P.]]
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[[Category: Phizackerley RP]]
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[[Category: Oxygen transport]]
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Current revision

STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION

PDB ID 1ith

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