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3kxg

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[[Image:3kxg.png|left|200px]]
 
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{{STRUCTURE_3kxg| PDB=3kxg | SCENE= }}
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==Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)==
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<StructureSection load='3kxg' size='340' side='right'caption='[[3kxg]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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===Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3kxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KXG FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21513497}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=K6X:3,4,5,6,7-PENTABROMO-1H-INDAZOLE'>K6X</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kxg OCA], [https://pdbe.org/3kxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kxg RCSB], [https://www.ebi.ac.uk/pdbsum/3kxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kxg ProSAT]</span></td></tr>
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[[3kxg]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
==See Also==
==See Also==
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*[[Casein kinase|Casein kinase]]
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021513497</ref><ref group="xtra">PMID:016298300</ref><ref group="xtra">PMID:017768728</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Franchin, C.]]
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[[Category: Franchin C]]
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[[Category: Papinutto, E.]]
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[[Category: Papinutto E]]
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[[Category: Atp-binding]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein kinase ck2-inhibitor complex]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)

PDB ID 3kxg

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