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3ixx
From Proteopedia
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| - | [[Image:3ixx.png|left|200px]] | ||
| - | + | ==The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53== | |
| - | + | <SX load='3ixx' size='340' side='right' viewer='molstar' caption='[[3ixx]], [[Resolution|resolution]] 15.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ixx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/West_Nile_virus West Nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IXX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 15Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixx OCA], [https://pdbe.org/3ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ixx RCSB], [https://www.ebi.ac.uk/pdbsum/3ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ixx ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3ixx]] is a 10 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/A7TZT4_WNV A7TZT4_WNV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ixx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ixx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Antibody|Antibody]] | + | *[[Antibody 3D structures|Antibody 3D structures]] |
| - | + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | |
| - | + | __TOC__ | |
| - | + | </SX> | |
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: West | + | [[Category: West Nile virus]] |
| - | [[Category: Cherrier | + | [[Category: Cherrier MV]] |
| - | [[Category: Chipman | + | [[Category: Chipman PR]] |
| - | [[Category: Diamond | + | [[Category: Diamond MS]] |
| - | [[Category: Fremont | + | [[Category: Fremont DH]] |
| - | [[Category: Holdaway | + | [[Category: Holdaway HA]] |
| - | [[Category: Kaufmann | + | [[Category: Kaufmann B]] |
| - | [[Category: Kostyuchenko | + | [[Category: Kostyuchenko VA]] |
| - | [[Category: Kuhn | + | [[Category: Kuhn RJ]] |
| - | [[Category: Lok | + | [[Category: Lok SM]] |
| - | [[Category: Nelson | + | [[Category: Nelson CA]] |
| - | [[Category: Nybakken | + | [[Category: Nybakken GE]] |
| - | [[Category: Rossmann | + | [[Category: Rossmann MG]] |
| - | [[Category: Warren | + | [[Category: Warren JT]] |
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Current revision
The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
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Categories: Large Structures | Mus musculus | West Nile virus | Cherrier MV | Chipman PR | Diamond MS | Fremont DH | Holdaway HA | Kaufmann B | Kostyuchenko VA | Kuhn RJ | Lok SM | Nelson CA | Nybakken GE | Rossmann MG | Warren JT
