3ixx

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m (Protected "3ixx" [edit=sysop:move=sysop])
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[[Image:3ixx.png|left|200px]]
 
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{{STRUCTURE_3ixx| PDB=3ixx | SCENE= }}
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==The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53==
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<SX load='3ixx' size='340' side='right' viewer='molstar' caption='[[3ixx]], [[Resolution|resolution]] 15.00&Aring;' scene=''>
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===The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ixx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/West_Nile_virus West Nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IXX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19713934}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixx OCA], [https://pdbe.org/3ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ixx RCSB], [https://www.ebi.ac.uk/pdbsum/3ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ixx ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3ixx]] is a 10 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXX OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/A7TZT4_WNV A7TZT4_WNV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ixx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ixx ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:019713934</ref><references group="xtra"/>
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</SX>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: West nile virus]]
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[[Category: West Nile virus]]
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[[Category: Cherrier, M V.]]
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[[Category: Cherrier MV]]
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[[Category: Chipman, P R.]]
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[[Category: Chipman PR]]
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[[Category: Diamond, M S.]]
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[[Category: Diamond MS]]
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[[Category: Fremont, D H.]]
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[[Category: Fremont DH]]
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[[Category: Holdaway, H A.]]
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[[Category: Holdaway HA]]
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[[Category: Kaufmann, B.]]
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[[Category: Kaufmann B]]
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[[Category: Kostyuchenko, V A.]]
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[[Category: Kostyuchenko VA]]
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[[Category: Kuhn, R J.]]
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[[Category: Kuhn RJ]]
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[[Category: Lok, S M.]]
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[[Category: Lok SM]]
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[[Category: Nelson, C A.]]
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[[Category: Nelson CA]]
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[[Category: Nybakken, G E.]]
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[[Category: Nybakken GE]]
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[[Category: Rossmann, M G.]]
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[[Category: Rossmann MG]]
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[[Category: Warren, J T.]]
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[[Category: Warren JT]]
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[[Category: Atp-binding]]
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[[Category: E53]]
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[[Category: Envelope protein]]
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[[Category: Fab]]
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[[Category: Fusion loop]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Icosahedral virus]]
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[[Category: Immature]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Rna replication]]
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[[Category: Transmembrane]]
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[[Category: Virion]]
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[[Category: Virus]]
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[[Category: West nile virus]]
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[[Category: Wnv]]
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Current revision

The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53

3ixx, resolution 15.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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