1fvp

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[[Image:1fvp.gif|left|200px]]<br /><applet load="1fvp" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1fvp, resolution 2.7&Aring;" />
 
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'''FLAVOPROTEIN 390'''<br />
 
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==Overview==
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==FLAVOPROTEIN 390==
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The three-dimensional structure of a flavoprotein, FP(390), from a luminescent bacterium, Photobacterium phosphoreum, solved by the molecular-replacement method, was refined to an R factor of 24.0% for 17 433 independent reflections, from 6.0 to 2.7 A resolution, collected by synchrotron radiation. The asymmetric unit of the crystal (space group P4(3)22, a = b = 76.8 and c = 242 A) contains two monomer molecules related by a non-crystallographic twofold axis to form a dimer. There are two Q-flavin [flavin mononucleotide (FMN) with myristic acid] molecules in FP(390) monomer. One of them is located at the interface of dimer which is bound to both monomer and the another is at the molecular surface. The electron density of myristic acids of Q-flavins at the dimer interface in both monomer are weak and unclear, showing the possibility that the Q-flavins bound in this site are not a single species but a mixture of two components, 6-(3"-myristic acid)-FMN and 6-(4"- myristic acid)-FMN.
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<StructureSection load='1fvp' size='340' side='right'caption='[[1fvp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1fvp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Photobacterium_phosphoreum Photobacterium phosphoreum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FVP FirstGlance]. <br>
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1FVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Photobacterium_phosphoreum Photobacterium phosphoreum] with <scene name='pdbligand=FMA:'>FMA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FVP OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMA:6-(3-TETRADECANOIC+ACID)+FLAVINE+MONONUCLEOTIDE'>FMA</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fvp OCA], [https://pdbe.org/1fvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fvp RCSB], [https://www.ebi.ac.uk/pdbsum/1fvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fvp ProSAT]</span></td></tr>
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Structure of flavoprotein FP390 from a luminescent bacterium Photobacterium phosphoreum refined at 2.7 A resolution., Kita A, Kasai S, Miyata M, Miki K, Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):77-86. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299728 15299728]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LUXF_PHOPO LUXF_PHOPO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/1fvp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fvp ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Photobacterium phosphoreum]]
[[Category: Photobacterium phosphoreum]]
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[[Category: Single protein]]
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[[Category: Kita A]]
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[[Category: Kita, A.]]
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[[Category: Miki K]]
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[[Category: Miki, K.]]
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[[Category: FMA]]
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[[Category: flavin-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:43:06 2008''
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Current revision

FLAVOPROTEIN 390

PDB ID 1fvp

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