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2v3i

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[[Image:2v3i.png|left|200px]]
 
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{{STRUCTURE_2v3i| PDB=2v3i | SCENE= }}
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==Hypocrea jecorina Cel7A in complex with (R)-dihydroxy-phenanthrenolol==
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<StructureSection load='2v3i' size='340' side='right'caption='[[2v3i]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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===HYPOCREA JECORINA CEL7A IN COMPLEX WITH (R)-DIHYDROXY-PHENANTHRENOLOL===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2v3i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V3I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.05&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=XX6:2-{[(2R)-2-HYDROXY-3-(9-PHENANTHRYLOXY)PROPYL]AMINO}PROPANE-1,3-DIOL'>XX6</scene></td></tr>
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[[2v3i]] is a 1 chain structure of [[Cellobiohydrolase]] and [[Glucanase]] with sequence from [http://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V3I OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v3i OCA], [https://pdbe.org/2v3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v3i RCSB], [https://www.ebi.ac.uk/pdbsum/2v3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v3i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v3i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v3i ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cellobiohydrolase|Cellobiohydrolase]]
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*[[Cellobiohydrolase 3D structures|Cellobiohydrolase 3D structures]]
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*[[Glucanase|Glucanase]]
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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[[Category: Cellulose 1,4-beta-cellobiosidase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Trichoderma reesei]]
[[Category: Trichoderma reesei]]
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[[Category: Berg, U.]]
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[[Category: Berg U]]
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[[Category: Fagerstrom, A.]]
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[[Category: Fagerstrom A]]
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[[Category: Sandgren, M.]]
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[[Category: Sandgren M]]
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[[Category: Stahlberg, J.]]
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[[Category: Stahlberg J]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Cellulose degradation]]
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[[Category: Chiral separation]]
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[[Category: Glycoprotein]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Polysaccharide degradation]]
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[[Category: Pyrrolidone carboxylic acid]]
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Current revision

Hypocrea jecorina Cel7A in complex with (R)-dihydroxy-phenanthrenolol

PDB ID 2v3i

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