1c02

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[[Image:1c02.png|left|200px]]
 
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{{STRUCTURE_1c02| PDB=1c02 | SCENE= }}
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==CRYSTAL STRUCTURE OF YEAST YPD1P==
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<StructureSection load='1c02' size='340' side='right'caption='[[1c02]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF YEAST YPD1P===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1c02]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C02 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10543964}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c02 OCA], [https://pdbe.org/1c02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c02 RCSB], [https://www.ebi.ac.uk/pdbsum/1c02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c02 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1c02]] is a 2 chain structure of [[Phosphotransferase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C02 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/YPD1_YEAST YPD1_YEAST] Phosphorelay intermediate protein that is part of the branched SLN1-YPD1-SKN7/SSK1 two-component regulatory system, which controls activity of the HOG1 pathway and gene expression in response to changes in the osmolarity of the extracellular environment. Catalyzes the phosphoryl group transfer from the membrane-bound osmosensing histidine kinase SLN1 to two distinct response regulator proteins, SSK1 in the cytoplasm, and transcription factor SKN7 in the nucleus.<ref>PMID:11073911</ref> <ref>PMID:9843501</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/1c02_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c02 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphotransferase|Phosphotransferase]]
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*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010543964</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Lee, J Y.]]
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[[Category: Lee JY]]
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[[Category: Lee, M G.]]
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[[Category: Lee MG]]
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[[Category: Song, H K.]]
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[[Category: Song HK]]
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[[Category: Suh, S W.]]
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[[Category: Suh SW]]
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[[Category: Helix-bundle]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF YEAST YPD1P

PDB ID 1c02

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