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1ntk

From Proteopedia

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[[Image:1ntk.png|left|200px]]
 
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{{STRUCTURE_1ntk| PDB=1ntk | SCENE= }}
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==Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1==
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<StructureSection load='1ntk' size='340' side='right'caption='[[1ntk]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ntk]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12885240}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AY1:[(2R,3S,6S,7R,8R)-3-[(3-FORMAMIDO-2-OXIDANYL-PHENYL)CARBONYLAMINO]-8-HEXYL-2,6-DIMETHYL-4,9-BIS(OXIDANYLIDENE)-1,5-DIOXONAN-7-YL]+2-METHYLPROPANOATE'>AY1</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntk OCA], [https://pdbe.org/1ntk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ntk RCSB], [https://www.ebi.ac.uk/pdbsum/1ntk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntk ProSAT]</span></td></tr>
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[[1ntk]] is a 11 chain structure of [[Cytochrome c]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTK OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/QCR1_BOVIN QCR1_BOVIN] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ntk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome c|Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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*[[Cytochrome bc1 3D structures|Cytochrome bc1 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012885240</ref><references group="xtra"/>
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Ubiquinol--cytochrome-c reductase]]
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[[Category: Large Structures]]
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[[Category: Esser, L.]]
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[[Category: Esser L]]
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[[Category: Gao, X.]]
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[[Category: Gao X]]
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[[Category: Quinn, B.]]
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[[Category: Quinn B]]
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[[Category: Wen, X.]]
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[[Category: Wen X]]
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[[Category: Xia, D.]]
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[[Category: Xia D]]
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[[Category: Yu, C A.]]
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[[Category: Yu C-A]]
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[[Category: Yu, L.]]
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[[Category: Yu L]]
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[[Category: Membrane protein]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1

PDB ID 1ntk

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