1stx

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[[Image:1stx.png|left|200px]]
 
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{{STRUCTURE_1stx| PDB=1stx | SCENE= }}
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==Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+==
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<StructureSection load='1stx' size='340' side='right'caption='[[1stx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1stx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1STX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1STX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15170321}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1stx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1stx OCA], [https://pdbe.org/1stx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1stx RCSB], [https://www.ebi.ac.uk/pdbsum/1stx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1stx ProSAT]</span></td></tr>
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[[1stx]] is a 6 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1STX OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/T2E5_ECOLX T2E5_ECOLX] Recognizes the double-stranded sequence GATATC and cleaves after T-3.
==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015170321</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Type II site-specific deoxyribonuclease]]
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[[Category: Large Structures]]
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[[Category: Horton, N C.]]
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[[Category: Horton NC]]
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[[Category: Perona, J J.]]
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[[Category: Perona JJ]]
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[[Category: Dna]]
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[[Category: Ecorv]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Restriction enzyme]]
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[[Category: X-ray crystallography]]
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Current revision

Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+

PDB ID 1stx

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