This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wl5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:17, 3 April 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1wl5.png|left|200px]]
 
-
{{STRUCTURE_1wl5| PDB=1wl5 | SCENE= }}
+
==Human cytosolic acetoacetyl-CoA thiolase==
-
 
+
<StructureSection load='1wl5' size='340' side='right'caption='[[1wl5]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-
===Human cytosolic acetoacetyl-CoA thiolase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1wl5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WL5 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15733928}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wl5 OCA], [https://pdbe.org/1wl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wl5 RCSB], [https://www.ebi.ac.uk/pdbsum/1wl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wl5 ProSAT]</span></td></tr>
-
[[1wl5]] is a 1 chain structure of [[Thiolase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WL5 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/THIC_HUMAN THIC_HUMAN]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/1wl5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wl5 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Thiolase|Thiolase]]
+
*[[Thiolase 3D structures|Thiolase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:015733928</ref><references group="xtra"/>
+
-
[[Category: Acetyl-CoA C-acetyltransferase]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Fukao, T.]]
+
[[Category: Large Structures]]
-
[[Category: Kondo, N.]]
+
[[Category: Fukao T]]
-
[[Category: Kursula, P.]]
+
[[Category: Kondo N]]
-
[[Category: Wierenga, R K.]]
+
[[Category: Kursula P]]
-
[[Category: Thiolase fold]]
+
[[Category: Wierenga RK]]
-
[[Category: Transferase]]
+

Current revision

Human cytosolic acetoacetyl-CoA thiolase

PDB ID 1wl5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools