3pok

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[[Image:3pok.png|left|200px]]
 
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{{STRUCTURE_3pok| PDB=3pok | SCENE= }}
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==Interleukin-1-beta LBT L3 Mutant==
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<StructureSection load='3pok' size='340' side='right'caption='[[3pok]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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===Interleukin-1-beta LBT L3 Mutant===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3pok]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3POK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21182275}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pok OCA], [https://pdbe.org/3pok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pok RCSB], [https://www.ebi.ac.uk/pdbsum/3pok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pok ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3pok]] is a 1 chain structure of [[Interleukin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POK OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref>
==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021182275</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allen, K N.]]
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[[Category: Large Structures]]
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[[Category: Barthelmes, K.]]
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[[Category: Allen KN]]
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[[Category: DeNunzio, N J.]]
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[[Category: Barthelmes K]]
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[[Category: Imperiali, B.]]
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[[Category: DeNunzio NJ]]
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[[Category: Jonker, H R.A.]]
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[[Category: Imperiali B]]
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[[Category: Peisach, E.]]
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[[Category: Jonker HRA]]
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[[Category: Reynolds, A M.]]
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[[Category: Peisach E]]
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[[Category: Schwalbe, H.]]
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[[Category: Reynolds AM]]
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[[Category: Beta trefoil]]
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[[Category: Schwalbe H]]
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[[Category: Cytokine]]
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[[Category: Extracellular membrane]]
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[[Category: Interleukin]]
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[[Category: Lanthanide tag]]
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[[Category: Receptor]]
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[[Category: Signaling]]
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Current revision

Interleukin-1-beta LBT L3 Mutant

PDB ID 3pok

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