3qep

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[[Image:3qep.png|left|200px]]
 
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{{STRUCTURE_3qep| PDB=3qep | SCENE= }}
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==RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside==
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<StructureSection load='3qep' size='340' side='right'caption='[[3qep]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qep]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QEP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21667997}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DFT:1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5MONOPHOSPHATE'>DFT</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qep OCA], [https://pdbe.org/3qep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qep RCSB], [https://www.ebi.ac.uk/pdbsum/3qep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qep ProSAT]</span></td></tr>
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[[3qep]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QEP OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021667997</ref><references group="xtra"/>
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[[Category: Escherichia phage RB69]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage rb69]]
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[[Category: Synthetic construct]]
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[[Category: Konigsberg, W H.]]
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[[Category: Konigsberg WH]]
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[[Category: Wang, J.]]
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[[Category: Wang J]]
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[[Category: Xia, S.]]
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[[Category: Xia S]]
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[[Category: Difluorotoluene nucleoside]]
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[[Category: Dttp]]
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[[Category: Transferase-dna complex]]
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[[Category: Triple mutant]]
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Current revision

RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside

PDB ID 3qep

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