3l7u

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[[Image:3l7u.png|left|200px]]
 
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{{STRUCTURE_3l7u| PDB=3l7u | SCENE= }}
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==Crystal structure of human NM23-H1==
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<StructureSection load='3l7u' size='340' side='right'caption='[[3l7u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Crystal structure of human NM23-H1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3l7u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[3l7u]] is a 3 chain structure of [[Nucleoside diphosphate kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7U OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7u OCA], [https://pdbe.org/3l7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7u RCSB], [https://www.ebi.ac.uk/pdbsum/3l7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NDKA_HUMAN NDKA_HUMAN] Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.<ref>PMID:2056128</ref> <ref>PMID:8810265</ref> <ref>PMID:12628186</ref>
==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Han, B G.]]
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[[Category: Han BG]]
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[[Category: Lee, B I.]]
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[[Category: Lee BI]]
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[[Category: Lee, S.]]
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[[Category: Lee S]]
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[[Category: Min, K.]]
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[[Category: Min K]]
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[[Category: Atp-binding]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Transferase]]
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[[Category: Tumor suppressor]]
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Current revision

Crystal structure of human NM23-H1

PDB ID 3l7u

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