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1el1

From Proteopedia

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[[Image:1el1.png|left|200px]]
 
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{{STRUCTURE_1el1| PDB=1el1 | SCENE= }}
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==X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE)==
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<StructureSection load='1el1' size='340' side='right'caption='[[1el1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1el1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EL1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_020080106}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1el1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1el1 OCA], [https://pdbe.org/1el1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1el1 RCSB], [https://www.ebi.ac.uk/pdbsum/1el1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1el1 ProSAT]</span></td></tr>
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[[1el1]] is a 2 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EL1 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC1_CANLF LYSC1_CANLF] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.[PROSITE-ProRule:PRU00680]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1el1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1el1 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020080106</ref><references group="xtra"/>
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[[Category: Canis lupus familiaris]]
[[Category: Canis lupus familiaris]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Koshiba, T.]]
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[[Category: Koshiba T]]
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[[Category: Nitta, K.]]
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[[Category: Nitta K]]
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[[Category: Tanaka, I.]]
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[[Category: Tanaka I]]
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[[Category: Yao, M.]]
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[[Category: Yao M]]
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[[Category: C-type lysozyme]]
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[[Category: Calcium binding lysozyme]]
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[[Category: Holo-form]]
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[[Category: Hydrolase]]
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Current revision

X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE)

PDB ID 1el1

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